Purtscher-like retinopathy in a 56-year-old Thai female with anti-glomerular basement membrane glomerulonephritis
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منابع مشابه
Anti-glomerular basement membrane glomerulonephritis in an HIV positive patient.
We report on a case of a patient with HIV infection, diagnosed 18 months prior to the development of an anti-glomerular basement membrane (anti-GBM) rapidly progressive glomerulonephritis; this is probably the first report of such an association. A 30-year-old white man presented with elevation of serum creatinine (1.3 - 13.5 mg/dL within one month). At admission, the urinalysis showed proteinu...
متن کاملChapter 14: Anti-glomerular basement membrane antibody glomerulonephritis
14.1: Treatment of anti-GBM GN 14.1.1: We recommend initiating immunosuppression with cyclophosphamide and corticosteroids plus plasmapheresis (see Table 31) in all patients with anti-GBM GN except those who are dialysis-dependent at presentation and have 100% crescents in an adequate biopsy sample, and do not have pulmonary hemorrhage. (1B) 14.1.2: Start treatment for anti-GBM GN without delay...
متن کاملBlockade of osteopontin inhibits glomerular fibrosis in a model of anti-glomerular basement membrane glomerulonephritis.
BACKGROUND In our rat model for anti-GBM GN, severe fibrosis follows glomerular inflammation. A potential role of extracellular matrix protein osteopontin (OPN) in glomerular fibrosis was investigated. METHODS Neutralizing OPN antiserum or control normal serum was injected into the experimental rats at late inflammatory/early fibrotic stage. Glomerular inflammation and fibrosis were determine...
متن کاملThe role of selectins in glomerular leukocyte recruitment in rat anti-glomerular basement membrane glomerulonephritis.
Leukocytes play a central role in the pathogenesis of anti-glomerular basement membrane glomerulonephritis (anti-GBM GN). Understanding the mechanisms underlying their recruitment in the glomerulus is of critical importance, because this may lead to more specific anti-inflammatory drug design. The requirement for integrins, especially from the beta2 group, and their Ig superfamily counter-recep...
متن کاملAnti-glomerular basement membrane antibodies.
Basement membranes form an anatomic barrier that contains connective tissue. They are composed of type IV collagen, laminin and proteoglycans. Anti-basement membrane antibodies bind to the non-collagen site of the α3 chain of type IV collagen. A group of renal diseases, pulmonary diseases and perhaps others affecting different organs have long been associated with the presence of antibodies dir...
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ژورنال
عنوان ژورنال: Asian Journal of Ophthalmology
سال: 2016
ISSN: 1560-2133,1560-2133
DOI: 10.35119/asjoo.v14i3.116